Journal of Dentistry and Bio-Allied Health Sciences

Register      Login

SEARCH WITHIN CONTENT

FIND ARTICLE

Volume / Issue

Online First

Related articles

VOLUME 1 , ISSUE 1 ( January-June, 2024 ) > List of Articles

ORIGINAL RESEARCH

Investigating the Role of Vitamin D Supplementation in Enhancing Periodontal Treatment Outcomes

Anita S Raikar, Kunal Keshaw, Devyani V Desai

Keywords : Clinical trial, Periodontal disease, Periodontal therapy, Supplementation, Vitamin D

Citation Information : Raikar AS, Keshaw K, Desai DV. Investigating the Role of Vitamin D Supplementation in Enhancing Periodontal Treatment Outcomes. J Dent bio allied Health Sci 2024; 1 (1):18-20.

DOI: 10.5005/jdbahs-11017-0009

License: CC BY-NC 4.0

Published Online: 19-06-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Abstract

Background: A common health problem, periodontal disease, causes inflammation and harm to the tissues that surround and support the teeth. Vitamin D insufficiency and the severity of periodontal disease may be related, according to new research. The purpose of this research is to find out whether taking vitamin D supplements improves the results of periodontal therapy. Materials and methods: One hundred people with a history of chronic periodontitis participated in a randomized controlled experiment. Vitamin D supplementation (1000 IU/day) and standard periodontal therapy were given to participants at random, or conventional periodontal therapy alone was given to the control group. At both the beginning and end of the 6-month treatment period, researchers assessed periodontal markers such as probing pocket depth (PPD) and clinical attachment level (CAL). Furthermore, vitamin D blood levels were measured both before and after the intervention. Results: A statistically significant difference was seen between the treatment group and the control group in terms of mean CAL (3.3 mm vs 4.8 mm) and PPD (5.2 mm vs 3.8 mm), respectively, at the conclusion of the trial. A considerable improvement in vitamin D serum levels (from 20 to 30 ng/mL) was seen in the treatment group, suggesting that supplementation was adhered to. When compared to the experimental group, the control group's blood vitamin D levels changed very little. Conclusion: It has been found that using vitamin D supplements in addition to traditional periodontal therapy can improve the effects of the treatment. Vitamin D may be useful as an adjuvant to periodontal therapy, as it significantly reduces PPD and CAL. In order to refine supplementation procedures and better understand the processes behind this association, more study is needed.


PDF Share
  1. Papapanou PN, Sanz M, Buduneli N, et al. Periodontitis: Consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J Periodontol 2018;89(Suppl 1):S173–S182. DOI: 10.1002/JPER.17-0721.
  2. Kassebaum NJ, Bernabé E, Dahiya M, et al. Global burden of severe periodontitis in 1990–2010: A systematic review and meta-regression. J Dent Res 2014;93(11):1045–1053. DOI: 10.1177/0022034514552491.
  3. Tonetti MS, Jepsen S, Jin L, et al. Impact of the global burden of periodontal diseases on health, nutrition and wellbeing of mankind: A call for global action. J Clin Periodontol 2017;44(5):456–462. DOI: 10.1111/jcpe.12732.
  4. Preshaw PM, Alba AL, Herrera D, et al. Periodontitis and diabetes: A two-way relationship. Diabetologia 2012;55(1):21–31. DOI: 10.1007/s00125-011-2342-y.
  5. Holick MF. Vitamin D deficiency. N Engl J Med 2007;357(3):266–281. DOI: 10.1056/NEJMra070553.
  6. Dietrich T, Joshipura KJ, Dawson-Hughes B, et al. Association between serum concentrations of 25-hydroxyvitamin D3 and periodontal disease in the US population. Am J Clin Nutr 2004;80(1):108–113. DOI: 10.1093/ajcn/80.1.108.
  7. Jimenez M, Giovannucci E, Krall Kaye E, et al. Predicted vitamin D status and incidence of tooth loss and periodontitis. Public Health Nutr 2014;17(4):844–852. DOI: 10.1017/S1368980013000177.
  8. Bashutski JD, Eber RM, Kinney JS, et al. The impact of vitamin D status on periodontal surgery outcomes. J Dent Res 2011;90(8):1007–1012. DOI: 10.1177/0022034511407771.
  9. Antonoglou GN, Suominen AL, Knuuttila M, et al. Associations between serum 25-hydroxyvitamin d and periodontal pocketing and gingival bleeding: Results of a study in a non-smoking population in Finland. J Periodontol 2015;86(6):755–765. DOI: 10.1902/jop. 2015.140262.
  10. WMA Declaration of Helsinki – Ethical principles for medical research involving human subjects. Available from: https://www.wma.net/policies-post/wma-declaration-of-helsinki-ethical-principles-for-medical-research-involving-human-subjects/.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.