Journal of Dentistry and Bio-Allied Health Sciences

Register      Login



Volume / Issue

Online First

Related articles

VOLUME 1 , ISSUE 1 ( January-June, 2024 ) > List of Articles


Comparative Evaluation of Different Toothpaste Formulations in Controlling Dental Plaque and Gingivitis

Shrivardhan Kalghatgi, Tanushri Dalvi, Chetan Patil, Pallavi Kamble

Keywords : Baking soda, Charcoal, Dental plaque, Fluoride, Gingivitis, Herbal, Natural, Oral hygiene, Toothpaste

Citation Information : Kalghatgi S, Dalvi T, Patil C, Kamble P. Comparative Evaluation of Different Toothpaste Formulations in Controlling Dental Plaque and Gingivitis. J Dent bio allied Health Sci 2024; 1 (1):12-14.

DOI: 10.5005/jdbahs-11017-0004

License: CC BY-NC 4.0

Published Online: 19-06-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Background: Maintaining oral hygiene is crucial for preventing dental plaque and gingivitis, both of which are common oral health issues. Toothpaste formulations play a significant role in controlling these conditions. This study aims to compare the effectiveness of various toothpaste formulations in controlling dental plaque and gingivitis. Materials and methods: A randomized controlled trial was conducted involving 100 participants with mild to moderate dental plaque and gingivitis. Participants were divided into five groups, each assigned to a different toothpaste formulation: fluoride-based, herbal, charcoal, baking soda, and natural. Plaque and gingivitis scores were assessed at baseline and after four weeks of regular toothbrushing with the assigned toothpaste. Plaque scores were measured using the Silness and Löe plaque index, while gingivitis scores were assessed using the Löe and Silness gingival index. Results: After four weeks, participants using fluoride-based toothpaste showed a significant reduction in plaque scores from a mean of 2.5 [standard deviation (SD) 0.8] to 1.2 (SD 0.5) (p < 0.001). Herbal toothpaste also demonstrated a reduction in plaque scores from 2.4 (SD 0.7) to 1.3 (SD 0.6) (p < 0.001). Charcoal, baking soda, and natural toothpaste showed reductions in plaque scores, but they were not statistically significant. Regarding gingivitis scores, fluoride-based toothpaste resulted in a significant decrease from 1.8 (SD 0.6) to 1.0 (SD 0.4) (p < 0.001). Other toothpaste formulations also showed reductions in gingivitis scores, but they were not statistically significant. Conclusion: Fluoride-based toothpaste demonstrated superior efficacy in controlling both dental plaque and gingivitis compared to other formulations. Herbal toothpaste also showed effectiveness in reducing plaque and gingivitis scores, albeit to a lesser extent. Charcoal, baking soda, and natural toothpaste formulations exhibited some reduction in plaque and gingivitis scores, but their effects were not statistically significant. Therefore, fluoride-based toothpaste remains the recommended choice for preventing dental plaque and gingivitis.

PDF Share
  1. Kassebaum NJ, Bernabé E, Dahiya M, et al. Global burden of severe periodontitis in 1990–2010: A systematic review and meta-regression. J Dent Res 2014;93(11):1045–1053. DOI: 10.1177/0022034514552491.
  2. Petersen PE, Ogawa H. The global burden of periodontal disease: Towards integration with chronic disease prevention and control. Periodontol 2000 2012;60(1):15–39. DOI: 10.1111/j.1600-0757.2011.00425.x.
  3. Marsh PD, Devine DA. How is the development of dental biofilms influenced by the host? J Clin Periodontol 2011;38(Suppl 11):28–35. DOI: 10.1111/j.1600-051X.2010.01673.x.
  4. Chapple IL, Van der Weijden F, Doerfer C, et al. Primary prevention of periodontitis: Managing gingivitis. J Clin Periodontol 2015;42 (Suppl 16):S71–S76. DOI: 10.1111/jcpe.12366.
  5. Walsh T, Worthington HV, Glenny AM, et al. Fluoride toothpastes of different concentrations for preventing dental caries. Cochrane Database Syst Rev 2019;3(3):CD007868. DOI: 10.1002/14651858.CD007868.pub3.
  6. Marinho VC, Higgins JP, Sheiham A, et al. Fluoride toothpastes for preventing dental caries in children and adolescents. Cochrane Database Syst Rev 2003;2003(1):CD002278. DOI: 10.1002/14651858.CD002278.
  7. Ferrazzano GF, Cantile T, Roberto L, et al. Determination of the in vitro and in vivo antimicrobial activity on salivary Streptococci and Lactobacilli and chemical characterisation of the phenolic content of a Plantago lanceolata infusion. Biomed Res Int 2015;2015:286817. DOI: 10.1155/2015/286817.
  8. Malhotra R, Grover V, Kapoor A, et al. Comparison of the effectiveness of a commercially available herbal mouthrinse with chlorhexidine gluconate at the clinical and patient level. J Indian Soc Periodontol 2011;15(4):349–352. DOI: 10.4103/
  9. American Dental Association. ADA Seal Products: Toothpastes. 2022. Available from:
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.